منابع مشابه
Formulation and Evaluation of Pioglitazone Hydrochloride Loaded Biodegradable Nanoparticles
The present study was aimed to develop and evaluate nanoparticulate containing pioglitazone HCl as potential antidiabetic drug delivery system. The pioglitazone HCl -loaded chitosan nanoparticles were prepared by ionic gelation of chitosan with tripolyphosphate anions at various concentrations. The nanoparticles were characterized by zeta potential analyzer; particle size analyzer and Fourier t...
متن کاملSimultaneous Estimation of Metformin Hydrochloride and Pioglitazone Hydrochloride by RPHPLC Method from Combined Tablet Dosage Form
A high performance reverse phase liquid chromatographic procedure is developed for simultaneous estimation of metformin hydrochloride and pioglitazone hydrochloride in combined tablet dosage form. The mobile phase used was a combination of acetonitrile:water:acetic acid (60:40:0.3) and the pH was adjusted to 5.5 by adding triethylamine. The detection of the combined dosage form was carried out ...
متن کاملFormulation and Evaluation of Multilayered Tablets of Pioglitazone Hydrochloride and Metformin Hydrochloride
In the treatment of type 2 diabetes mellitus a continuous therapy is required which is a more complex one. As in these patients there may be a defect in both insulin secretion and insulin action exists. Hence, the treatment depends on the pathophysiology and the disease state. In the present study, multilayered tablets of pioglitazone hydrochloride 15 mg and metformin hydrochloride 500 mg were ...
متن کاملSensitive Determination of Related Substances in Pioglitazone Hydrochloride by Hplc
Objective: An efficient, high performance liquid chromatographic method has been developed and validated for the quantification of related substances in pioglitazone hydrochloride drug substance. Methods: This method includes the determination of three related substances in pioglitazone hydrochloride. The mobile phase A is 0.1% w/v triethylamine in water with pH 2.5 adjusted by dilute phosphori...
متن کاملPioglitazone on Lipid and Glycemic Control Effects of Pioglitazone Hydrochloride on Japanese Patients with Type 2 Diabetes Mellitus
Department of Internal Medicine, School of Medicine, Teikyo University, Tokyo, Japan. Department of Internal Medicine, Metabolism, Endocrinology, and Atherosclerosis University of Tsukuba, Ibaraki prefecture, Japan. Department of Internal Medicine, Sakura Medical Center, School of Medicine, Toho University, Chiba, Japan. Department of Clinical Cell Biology Graduate School of Medicine, Chiba Uni...
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ژورنال
عنوان ژورنال: Acta Crystallographica Section E Structure Reports Online
سال: 2004
ISSN: 1600-5368
DOI: 10.1107/s1600536804033100